Re: starship-design: Suspended Animation

[Antonio C T Rocha <arocha@bsb.nutecnet.com.br>]

Ooops! Sorry about the HTML attachment to the previous message. Got carried away and overlooked the caveat against it. My apologies.

Here are a few marginally comprehensible (and slightly relevant) article among a store of 100s just found relating to present studies in hibernation..
Can hardly wait 50 years. Figure hibernation assisted cold storage is going to be The fad for the terminally ill by then. Move over, Walt. :)

URLs:

Water use during hibernation in ground squirrels.
  http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6998740&form=6&db=m&Dopt=b

Similarities and gradations between deep-sleep, hypothermia, and hibernation regarding energy conservation.
  http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6395910&form=6&db=m&Dopt=b

Dogs lung extended preservation for transplants using ground squirrel hibernation trigger compounds! The idea is to eventually use it for human lung transplants.
  http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8633964&form=6&db=m&Dopt=b

Slower aging during hibernation.
  http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7221552&form=6&db=m&Dopt=b
And sleep.
  http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=162800&form=6&db=m&Dopt=b


Hibernation could mitigate infections?!
  http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6538934&form=6&db=m&Dopt=b

That ought to do it for now.

Antonio

Title: PubMed medline query

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Fed Proc 1980 Oct;39(12):2969-2973

Water metabolism and renal function during hibernation and hypothermia.

Deavers DR, Musacchia XJ

Total water turnover in normothermic, cold-exposed 13-lined ground squirrels was about half that predicted from allometric relationships of water loss and body weight. During hibernation pulmocutaneous water loss and oxygen consumption were 1/77th and 1/52nd of values during normothermia, respectively, in this species. Renal function during deep torpor with body temperatures of 8 C or lower has also been assessed in ground squirrels and hamsters. The weight of evidence suggests that glomerular filtration and urine formation are absent of undetectable in these animals. We feel that the reduction in arterial blood pressure may be the primary adaptation for eliminating filtration. If filtration (which is not thermally vulnerable, being dependent on hydrostatic pressure) occurred, it is difficult to imagine how reabsorption (which has critical metabolic steps such as ion transport that would be thermally vulnerable) could keep pace. Filtration and hypertonic urine formation occur at body temperatures of 20 to 30 C during the arousal process. Marmots differ from other hibernating rodents in that measurable filtration and hypertonic urine formation occurs during hibernation.

Publication Types:

• Review

PMID: 6998740, UI: 81024350

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